Biological Sciences (BIOS)
Prerequisites: Biological Sciences Major and freshman or sophomore standing
Description: An orientation to the Biological Sciences Major. Introduction to advising and university services, study skills, professionalism, community building, and career development.
Prerequisites: Parallel registration in BIOS 101L. Credit toward the degree cannot be earned in both BIOS 101 and BIOS 110.
High school chemistry strongly recommended. Not intended for most Life Sciences majors; such students should take LIFE 120-LIFE 120L and LIFE 121-LIFE 121L instead. BIOS 101 does not count in the Biological Sciences major.
Description: Analysis of the structure, functions, and interactions of organisms from the molecular to the ecosystem levels.
Prerequisites: Parallel registration in BIOS 110L. Credit toward the degree cannot be earned in both BIOS 101 and BIOS 110.
High school chemistry or equivalent strongly recommended. Not intended for most Life Sciences majors; such students should take LIFE 120-LIFE 120L and LIFE 121-LIFE 121L instead. BIOS 110 does not count in the Biological Sciences major.
Description: Introduction to biology with a focus on organization of molecules and cells to the level of human body systems; basic structure (anatomy) and function (physiology) of human tissues, organs and organ systems; reproduction, genetics; DNA technology and genetic engineering.
Prerequisites: Parallel registration in BIOS 110. Credit toward the degree cannot be earned in both BIOS 101L and BIOS 110L.
BIOS 110L does not count in the Biological Sciences major.
Description: Hands-on lab exercises to understand biological concepts of human organization from molecules to cells to the body systems, basic structure and function of human tissues, organs, organ systems, reproduction, genetics, as well as DNA technology and genetic engineering.
Description: Identification of representative orders and families of insects by their anatomy, metamorphosis, habits and habitats. Sight recognition emphasized but dichotomous keys also used. Interrelation of insect and habitats stressed.
Prerequisites: By permission
Description: Perform original research by using the scientific method to isolate a virus that infects a harmless bacterium (bacteriophage) from local soil samples. Lab skills acquired include pipetting, aseptic technique, and serial dilutions; use basic DNA and electron microscopy analyses to characterize the phage.
This course is a prerequisite for: BIOS 137
Prerequisites: BIOS 136 and by permission.
Description: Build on an original project involving isolation of a virus that infects a harmless bacterium (bacteriophage) using bioinformatic tools to analyze and annotate the sequenced bacteriophage genome.
Prerequisites: Permission.
Open to Biological Sciences Learning Community students only.
Description: An exploration of biological sciences for undergraduates in the Biological Sciences Learning Community. Topics vary.
Prerequisites: Good standing in the University Honors Program.
Description: Topic varies.
Prerequisites: BIOS 206 or parallel
Description: Series of lab exercises to introduce principles of genetic, molecular and cellular biology. Experiments done using model systems to identify, map and clone genes; analyze gene products and expression; and fractionate cell components.
This course is a prerequisite for: FORS 401
Description: Inheritance and regulation of genes in organisms and populations. Fundamentals of genomics and bioinformatics.
This course is a prerequisite for: AGRO 815, PLAS 415; ASCI 330; ASCI 486; BIOC 433H; BIOS 99; BIOS 205; BIOS 302; BIOS 303; BIOS 326; BIOS 420, BIOS 820, VBMS 820, MBIO 420; BIOS 421, BIOS 821, MBIO 421; BIOS 443, BIOS 843, VBMS 843, MBIO 443, VBMS 443; BIOS 802, BIOS 402; FORS 401; NUTR 820, NUTR 420; PLPT 418, PLPT 818, MBIO 418
Description: Introduction to the principles and processes of ecology and evolution. Structure and dynamics of populations and communities; biotic and abiotic interactions; mechanisms of evolutionary change; natural selection; adaptation; and speciation.
Prerequisites: A grade of C, P, or better in BIOS 101 and 101L or BIOS 110 and 110L or LIFE 120 and 120L; Parallel registration in BIOS 213L
Description: Elementary survey of the basic functional systems of the human body: the muscular, nervous, receptor, circulatory, respiratory, digestive, excretory, endocrine, and reproductive systems.
Prerequisites: Sophomore standing.
Cadaver prosections are studied in the lab. Letter Grade Only.
Description: Introduction to the major organ systems of the human body including skeletal, major muscle, nervous, digestive, circulatory, excretory, and reproductive systems. Anatomical structures as they pertain to clinical anatomy.
Description: Topics vary.
Prerequisites: Permission
A maximum of 3 credit hours may be counted toward the major in BIOS. Before registering, arrangements must be made with a faculty member in BIOS to reach an agreement on the scope and determine the amount of credit for the project.
Description: Independent work directed by faculty.
Prerequisites: One semester BIOS and one semester CHEM
Description: Introduction to the principles of toxicology as they apply to environmental contaminants, agri-chemicals, and industrial and naturally occurring chemicals.
Prerequisites: BIOS 206
Description: Molecular biology of prokaryotes and eukaryotes. Review of the experimental basis for the principles of the discipline.
Prerequisites: A grade of C, P, or better in LIFE 121 and LIFE 121L; CHEM 251 or CHEM 255 or CHEM 261.
Credit towards the degree may not be earned in both BIOS 313 and 314. BIOS 206 and parallel registration in BIOS 312 recommended.
Description: Traditional microbiology techniques without recombinant DNA methods.
Field trips are required and may occur outside of scheduled class time.
Description: Introduction to the basic principles and concepts of the biology of plants. Adaptive variation and biodiversity of plants considering the relationships of plant structure to function integrating across succeeding levels of organization: molecule, cell, tissue, organism, organism, population, community, and ecosystem.
Description: Provides a broad overview of bioinformatics. Shows how bioinformatics can help solving problems in biological research. Covered topics: biological databases, molecular biology tools, sequence comparison methods, phylogenetic inference, and molecular graphics.
Prerequisites: LIFE 121
Description: Introduction to the use of plants in traditional and alternative medicine, nutrition, and wellness. Examination of the biological, historical, and cultural origins of plant medicinal compounds used to enhance wellness or treat human diseases, such as cancer and heart disease. Consideration of the social and ethical consequences of the development of plant-derived drugs, use of herbal remedies in wellness and nutrition and of other emerging issues associated with plants in human medicine.
Description: Emphasis on parasitic diseases of humans. Impact of parasitism on societies considered in addition to the clinical consequences for infected individuals. Means of transmission, diagnosis, and treatment considered in respect to recent technological advances in production of monoclonal antibodies and genetic engineering. Nature and biological significance of parasitism are viewed in terms of prospects for control.
Prerequisites: Permission
Description: Combination of work outside the University and academic work in biological sciences arranged through the Career Services Office.
Prerequisites: Permission
Open to students who are interested in life sciences education and want to train to become a Teaching Assistant or Learning Assistant in the School of Biological Sciences. Students must have earned a grade of C or better in the BIOS or LIFE course they will assist in.
Description: A structured training experience in the professional skills used by teaching and learning assistants in life science laboratories, recitations and lectures.
Prerequisites: Permission
Open only to students who expect to become teaching assistants in anatomy or physiology
Description: A combination of academic work and instruction in the anatomy or physiology laboratories in biological sciences: cadaver dissection or work with physiological equipment; assist in the instruction of anatomical and physiological concepts.
Description: Exploring the biology of plant pathogens, pathogen-host plant interactions, and environmental influences on plant diseases. Examining cultural, chemical, and biological strategies, along with host resistance, for plant disease management. Builds on topics covered in PLPT 210, with additional emphasis on the strategies employed by the four major groups of plant pathogens, plant responses to disease-causing organisms, and approaches to disease management.
Prerequisites: BIOS 206 and Senior standing
Description: Principles of cancer genetics, cancer prevention, and new methods for diagnosis and therapy. Fundamentals of the cell and molecular events that lead to human cancer.
Description: Microscopic anatomy of the tissues and organs of major vertebrate species, including humans. Normal cellular arrangements of tissues and organs as related to their macroscopic anatomy and function, with reference to sub-cellular characteristics and biochemical processes. Functional relationships among cells, tissues, organs and organ systems, contributory to organismal well being. General introduction to pathological processes and principles underlying some diseases.
Prerequisites: BIOS 206 and Senior standing
Description: Genetic basis of human variation, with emphasis on methods of applying genetic principles to humankind. Genetic ratios in pooled data; population and quantitative genetics; consanguinity; polygenic inheritance; blood types; sex linkage; linkage and crossing over; sex determination; visible chromosome variation; mutation; heredity and environment; eugenics; anthropological genetics; molecular genetics and molecular basis of disease; human genome project.
Description: Basic conservation science theory and conservation decision making tools which are essential for making effective decisions for biodiversity conservation. Topics include systematic conservation planning, population viability analysis, risk assessment, and applying those tools to real conservation problems.
Prerequisites: BIOS 206 and Senior standing
Description: In-depth study of the principles and methodology of genetics, with emphasis on Drosophila: multiple alleles and complex loci, linkage and recombination, chromosome rearrangements, fine structure analysis, sex determination, recombinant DNA, and gene function in development.
Prerequisites: BIOS 206 and Senior standing
Description: Molecular basis of genetics. Gene structure and regulation, transposable elements, chromosome structure, DNA replication, and repair mechanisms and recombination.
Description: Diversity of microbial cell composition, structure, and function enabling movement, metabolism, symbiosis, and adaptation using bacterial, fungal, algal, and viral examples. A physiological, biochemical and molecular approach used throughout.
Prerequisites: BIOS 213
Description: Comprehensive survey of comparative physiology with emphasis on the diversity of adaptations in basic physiological systems and the effects of environmental parameters upon such systems. Comparative physiology of osmoregulation, temperature regulation, metabolism, muscle, central nervous function, and sensory function.
Prerequisites: Parallel registration in BIOS 422/822
Letter grade only.
Description: Physiological adaptations in ecological and evolutionary context.
Prerequisites: 12 hrs GEOL or BIOS.
Description: Analysis and interpretation of the Quaternary period's paleoecological data. Patterns of long-term climate variation. Distribution patterns and responses of organisms and ecosystems to Quaternary environmental change.
Description: Chemical cycling at or near the earth's surface, emphasizing interactions among the atmosphere, biosphere, geosphere and hydrosphere. Modern processes, the geological record, and human impacts on elemental cycles.
Prerequisites: BIOS 206
Description: Introduction to the use of plants for basic and applied purposes by deliberate manipulation of their genomes; techniques in plant genetic engineering; manipulations of plant development and metabolism; engineering pest, disease, and stress resistance; plants as bioreactors; and environmental and social impacts of plant biotechnology.
Prerequisites: LIFE 120 and LIFE 121 or BIOS 101; STAT 218 or STAT 380 or EDPS 459 or PSYC 350 or ECON 215.
Description: Fundamentals of the analysis of high throughput experiments to understand complex biological systems. Principles and methods such as next generation sequencing, protein-protein interaction networks, regulatory networks, and biological data mining and integration. Emerging research in new biotechnology and data analysis in biomedical and life sciences.
Prerequisites: BIOS 206
No computer programming skill is required.
Description: Basic knowledge and skills needed for general bioinformatics, genomics and proteomics analyses. Various computational analyses including database search, sequence alignment, phylogenetic reconstruction, gene prediction/mining, microarray data analyses and protein structure analyses.
Prerequisites: BIOS 207 and Senior standing
Description: Principles of phylogenetic inference and emphasis on the application of phylogenetic hypotheses in biology and the biomedical sciences. How inferences derived from phylogenetic trees can be applied in different areas of biological investigation including systematics, biogeography, conservation biology, molecular evolution, genome structure, epidemiology, population biology, ecology, character evolution, behavior, and macroevolution.
Prerequisites: BIOS 207
Students must have at least one afternoon available for running a middle school science club (typically between 3-5pm). Background checks required.
Description: Introduction to science communication, formal versus informal science education, and best practices in informal science education. Review of state and national science standards and how students learn. Introduction to informal science practitioners and facilities in Nebraska. Role playing and development and implementation of hands on, inquiry-based science activities. Training in evaluation and assessment.
Prerequisites: LIFE 120 with a grade of C or better; CHEM 252 or CHEM 262 with a grade of C or better.
BIOS 206 or PLAS 215 is recommended. First course of a two-semester, comprehensive biochemistry course sequence.
Description: Structure and function of proteins, nucleic acids, carbohydrates and lipids; nature of enzymes; major metabolic pathways of catabolism; and biochemical energy production.
This course is a prerequisite for: AGRO 810, BIOC 810, HORT 810; ASCI 820; ASCI 917; ASCI 925, NUTR 925; ASCI 926, NUTR 926; ASCI 927, NUTR 927; BIOC 305; BIOC 390; BIOC 432, BIOC 832, BIOS 432, CHEM 432, CHEM 832, BIOS 832; BIOC 433, BIOC 833, BIOS 433, BIOS 833, CHEM 433, CHEM 833; BIOC 433H; BIOC 440; FDST 470, FDST 870; NUTR 450; NUTR 455; NUTR 820, NUTR 420; NUTR 821; PLAS 434, BIOC 434, BIOS 434, CHEM 434, AGRO 834, BIOC 834, BIOS 834, CHEM 834; VBMS 410; VBMS 805; VBMS 950
Description: Introduction to techniques used in biochemical and biotechnology research, including measurement of pH, spectroscopy, analysis of enzymes, chromatography, fractionation of macromolecules, electrophoresis, and centrifugation.
Prerequisites: BIOC/BIOS/CHEM 431/831.
Description: Biochemical metabolism unique to plants. Relationships of topics previously acquired in general biochemistry to biochemical processes unique to plants. Biochemical mechanisms behind physiological processes discussed in plant or crop physiology.
Prerequisites: BIOS 207 and senior standing
Description: Application of evolutionary tools to biomedical questions. Managing the evolution of drug resistance and pathogen virulence. Evolutionary principles of vaccine design. Emerging infectious disease. Human evolutionary history. Life-history trade-offs in human evolution. Parent-offspring and parent-parent conflict. Mismatch hypothesis. Hygiene hypothesis.
Prerequisites: BIOS 207
Description: Species-area relationships, latitudinal gradients in species richness, abundance diversity relationships, ecological scaling relationships with body size, community assembly, evolutionary dynamics, climate change, and human impacts on the ecology of the Anthropocene.
Prerequisites: BIOC/BIOS/CHEM 433/833.
Description: Methods approach to systems biology analysis. Molecular identification and quantification employing techniques such as mass spectrometry, chromatography, electrophoretic fractionation, transcriptomics, protemics and metabolomics. Data and pathway analysis with computational methods.
This course is a prerequisite for: VBMS 919
Letter grade only.
Description: To introduce and integrate, students in biochemistry and other life sciences, to the field of computational modeling of biochemical and biological network systems into a seamless curriculum.
Prerequisites: BIOS 312
Description: Fundamental principles involved in host-microorganism interrelationships. Identification of pathogens, isolation, propagation, mode of transmission, pathogenicity, symptoms, treatment, prevention of disease, epidemiology, and methods of control.
Prerequisites: A course in vertebrate physiology and/or biochemistry.
Description: Mammalian endocrine glands from the standpoint of their structure, their physiological function in relation to the organism, the chemical nature and mechanisms of action of their secretory products, and the nature of anomalies manifested with their dysfunction.
Description: Fundamental consideration of cellular and humoral mechanisms of immunity, the structure and function of immunoglobulins, antigen-antibody interactions; hypersensitivity; transplantation and tumor immunity; immune and autoimmune disorders.
Prerequisites: 3 hours of BIOS or 3 hours of LIFE; 3 hours of CHEM
Description: An introduction into the role that microorganisms play and have played in natural and man-made environments. Topics covered include microbial diversity and physiology in soil, sediment, and water; microbes in Earth history; biogeochemical cycling; mineral formation and dissolution; biodegradation and bioremediation; biotechnology.
Prerequisites: BIOS 312
Description: Nature, physiology, and interactions of microorganisms in foods. Introduction to food-borne diseases, the effect of food processing systems on the microflora of foods, principles of food preservation, food spoilage, and foods produced by microorganisms. Food plant sanitation and criteria for establishing microbial standards for food products.
Description: Overview of the key traits, relationships and evolutionary dynamics of invertebrate animals over Earth's history, particularly over the Phanerozoic (i.e., the last 540 million years). Emphasis on the use of invertebrate fossil record to test ideas about long term evolutionary patterns as well as learning the histories and basic anatomies of major invertebrate taxa.
Description: Conservation and management of native and invasive predators. Functional and numerical responses. Evolution of predator-prey interactions. Optimal foraging. Modeling predator-prey population dynamics. Trophic cascades. Prey defenses against predation.
Description: Nature and characteristics of populations and communities. Interactions within and between populations in community structure and dynamics. Direct and indirect interactions and ecological processes, competition, predation, parasitism, herbivory, and pollination. Structure, functioning and persistence of natural communities, foodweb dynamics, succession, and biodiversity.
Description: Biological systems, from molecules to ecosystems, are analyzed using mathematical techniques. Strengths and weaknesses of mathematical approaches to biological questions. Brief review of college level math; introduction to modeling; oscillating systems in biology; randomness in biology; review of historically important and currently popular models in biology.
Description: Processes controlling the cycling of energy and elements in ecosystems and how both plant and animal species influence them. Human-influenced global and local changes that alter these cycles and ecosystem functioning.
Prerequisites: CHEM 109A and 109L and CHEM 110A and 110L, or CHEM 105A and 105L and CHEM 106A and 106L; Junior or Senior Standing.
Offered even-numbered calendar years.
Description: Physical, chemical and biological processes that occur in wetlands; the hydrology and soils of wetland systems; organisms occurring in wetlands and their ecology wetland creation, delineation, management and ecotoxicology.
Description: Physical, chemical, and biological processes that occur in fresh water. Organisms occurring in fresh water and their ecology; biological productivity of water and its causative factors; eutroplication and its effects.
Prerequisites: Senior standing.
Recommend having a strong science background, including courses from the agronomic, environmental, microbiology, engineering or medicine disciplines.
Description: Soil from a microbe's perspective-growth, activity and survival strategies; principles governing methods to study microorganisms and biochemical processes in soil; mechanisms controlling organic matter cycling and stabilization with reference to C, N, S, and P; microbial interactions with plants and animals; and agronomic and environmental applications of soil microorganisms.
Description: Introduction to animal behavior stressing the ethological approach. Anatomical and physiological bases of behavior, ontogenetic and phylogenetic observations, and the relations of animal behavior studies to genetics, ecology, taxonomy, and evolution.
Prerequisites: PSYC 273
Description: Relationship of physiological variables to behavior, an introduction to laboratory techniques in neuropsychology.
Description: Overview of the diversity of plants and algae, with emphasis on phylogenetic relationships, the evolution of important physical and genomic characteristics, principles of plant classification and identification, and modern methods of plant molecular systematics. Lab work on taxonomic analysis and plant identification.
Prerequisites: BIOS 207 and Senior standing
Description: The principles and processes of micro- and macroevolution. Mechanisms behind evolutionary change and examples of these processes in a wide variety of organisms.
Prerequisites: NRES/BIOS 386
Description: Fossil and living amphibians and reptiles. Anatomy, classification, ecology and evolution.
May also be offered at Cedar Point Biological Station.
Description: Biology of birds emphasizing the behavior and ecology of this group. Topics include avian diversity, systematics & evolutionary history, flight, foraging, migration, communication, reproductive biology, population ecology and conservation biology.
Prerequisites: Parallel registration in BIOS 475/875
Description: Avian field identification in diverse prairie, riparian, and montane habitats. Individual studies of foraging behavior, territoriality, anti-predator behavior, mating systems, or nesting ecology.
May also be offered at Cedar Point Biological Station. Field trips are required and may occur outside of scheduled class time. Lab and field time emphasize diversity of mammalian families and species identification of Nebraska mammals.
Description: Evolution, natural history, ecology, and functional morphology of planetary mammals and mammals of the Northern Great Plains.
Statistics course recommended.
Description: Pairwise and multiple alignments, sequence similarity and domain search, distance estimation, phylogenetic methods, gene mining, protein classification and structure. Algorithms used in bioinformatics as well as fundamental concepts of molecular evolution that underlie various bioinformatics methods.
Prerequisites: 8 hrs biological sciences
Description: Development, structure, and function of tissues and organs of the higher plants. Relationships of structure to physiology and ecology of plants.
Prerequisites: NRES 222 or equivalent
Description: Fundamental physical drivers operating in stream and river ecosystems and how those vary in space and time. Major classes of organisms associated with stream ecosystems and their functional roles. Fundamental controls on biotic diversity in stream and river ecosystems and its variance. Major aspects of stream ecosystem function including energy flow and nutrient cycling. Ecosystem services provided by stream and river ecosystems and causes and consequences of human impacts on streams and rivers. Underlying principles of bioassessment and current methods of stream restoration.
Prerequisites: Permission.
Four credit hours may be counted toward the undergraduate BIOS major. Before registering, arrangements must be made with a School of Biological Sciences faculty member to reach an agreement on the scope and to determine the amount of credit for the project.
Description: Independent study and laboratory or field investigation of a specific problem.
Prerequisites: Permission.
Description: Independent research leading to a thesis.
Prerequisites: Permission
Description: Independent research leading to an honors thesis.