Description: Principles of cancer genetics, cancer prevention, and new methods for diagnosis and therapy. Fundamentals of the cell and molecular events that lead to human cancer.
Description: Micro- and macroevolutionary patterns and processes. Population genetics, evolutionary ecology, speciation, phylogenetic systematics, and biogeographic patterns of extant and extinct taxa.
Description: Ecological principles at the populations, community, and ecosystem levels. Population growth, meta-population dynamics, competitive and predatory interactions, temporal and spatial variation in community food webs, tropic cascades, patterns and mechanisms underlying species diversity, ecosystem processes, nutrient cycling, and global change.
This course is a prerequisite for: BIOS 955
Description: Regulation and timing of macromolecular synthesis during the cell cycle; the genetic autonomy of mitochondria and chloroplasts.
Description: Microscopic anatomy of the tissues and organs of major vertebrate species, including humans. Normal cellular arrangements of tissues and organs as related to their macroscopic anatomy and function, with reference to sub-cellular characteristics and biochemical processes. Functional relationships among cells, tissues, organs and organ systems, contributory to organismal well being. General introduction to pathological processes and principles underlying some diseases.
Pass/No Pass only.
Description: Discussion of skills needed to be a professional scientist including: writing, submitting, editing, and revision of journal articles and grant proposals; preparation or oral and poster presentations; and ethical issues in research and teaching.
Description: Survey of techniques used in plant cell, tissue and organ culture, including current research. Laboratory emphasizes practical manipulation of plant cells, tissues, and organs, including examples from woody and herbaceous plant species.
Description: Genetic basis of human variation, with emphasis on methods of applying genetic principles to humankind. Genetic ratios in pooled data; population and quantitative genetics; consanguinity; polygenic inheritance; blood types; sex linkage; linkage and crossing over; sex determination; visible chromosome variation; mutation; heredity and environment; eugenics; anthropological genetics; molecular genetics and molecular basis of disease; human genome project.
Description: Survey of topics in developmental biology, both animal and plant development.
Description: Basic conservation science theory and conservation decision making tools which are essential for making effective decisions for biodiversity conservation. Topics include systematic conservation planning, population viability analysis, risk assessment, and applying those tools to real conservation problems.
Description: In-depth study of the principles and methodology of genetics, with emphasis on Drosophila: multiple alleles and complex loci, linkage and recombination, chromosome rearrangements, fine structure analysis, sex determination, recombinant DNA, and gene function in development.
Description: Diversity of microbial cell composition, structure, and function enabling movement, metabolism, symbiosis, and adaptation using bacterial, fungal, algal, and viral examples. A physiological, biochemical and molecular approach used throughout.
Prerequisites: BIOS 213
Description: Comprehensive survey of comparative physiology with emphasis on the diversity of adaptations in basic physiological systems and the effects of environmental parameters upon such systems. Comparative physiology of osmoregulation, temperature regulation, metabolism, muscle, central nervous function, and sensory function.
Prerequisites: 12 hrs GEOL or BIOS.
Description: Analysis and interpretation of the Quaternary period's paleoecological data. Patterns of long-term climate variation. Distribution patterns and responses of organisms and ecosystems to Quaternary environmental change.
Description: Introduction to the use of plants for basic and applied purposes by deliberate manipulation of their genomes; techniques in plant genetic engineering; manipulations of plant development and metabolism; engineering pest, disease, and stress resistance; plants as bioreactors; and environmental and social impacts of plant biotechnology.
Description: Fundamentals of the analysis of high throughput experiments to understand complex biological systems. Principles and methods such as next generation sequencing, protein-protein interaction networks, regulatory networks, and biological data mining and integration. Emerging research in new biotechnology and data analysis in biomedical and life sciences.
Prerequisites: BIOS 206
No computer programming skill is required.
Description: Basic knowledge and skills needed for general bioinformatics, genomics and proteomics analyses. Various computational analyses including database search, sequence alignment, phylogenetic reconstruction, gene prediction/mining, microarray data analyses and protein structure analyses.
Prerequisites: BIOS 207 and Senior standing.
Description: Principles of phylogenetic inference and emphasis on the application of phylogenetic hypotheses in biology and the biomedical sciences. How inferences derived from phylogenetic trees can be applied in different areas of biological investigation including systematics, biogeography, conservation biology, molecular evolution, genome structure, epidemiology, population biology, ecology, character evolution, behavior, and macroevolution.
Prerequisites: BIOS 207.
Students must have at least one afternoon available for running a middle school science club (typically between 3-5pm). Background checks required.
Description: Introduction to science communication, formal versus informal science education, and best practices in informal science education. Review of state and national science standards and how students learn. Introduction to informal science practitioners and facilities in Nebraska. Role playing and development and implementation of hands on, inquiry-based science activities. Training in evaluation and assessment.
Description: Structure and function of proteins, nucleic acids, carbohydrates and lipids; nature of enzymes; major metabolic pathways of catabolism; and biochemical energy production.
Continuation of BIOC 431/831.
Description: Major metabolic pathways of anabolism, structural and biochemical aspects of biological information flow and use in biotechnology.
Description: Introduction to techniques used in biochemical and biotechnology research, including measurement of pH, spectroscopy, analysis of enzymes, chromatography, fractionation of macromolecules, electrophoresis, and centrifugation.
Prerequisites: BIOC/BIOS/CHEM 431/831.
Description: Biochemical metabolism unique to plants. Relationships of topics previously acquired in general biochemistry to biochemical processes unique to plants. Biochemical mechanisms behind physiological processes discussed in plant or crop physiology.
Prerequisites: BIOS 207
Description: Application of evolutionary tools to biomedical questions. Managing the evolution of drug resistance and pathogen virulence. Evolutionary principles of vaccine design. Emerging infectious disease. Human evolutionary history. Life-history trade-offs in human evolution. Parent-offspring and parent-parent conflict. Mismatch hypothesis. Hygiene hypothesis.
Prerequisites: BIOC/BIOS/CHEM 433/833, or permission.
Description: Methods approach to systems biology analysis. Molecular identification and quantification employing techniques such as mass spectrometry, chromatography, electrophoretic fractionation, transcriptomics, protemics and metabolomics. Data and pathway analysis with computational methods.
Prerequisites: BIOS 312.
Description: Fundamental principles involved in host-microorganism interrelationships. Identification of pathogens, isolation, propagation, mode of transmission, pathogenicity, symptoms, treatment, prevention of disease, epidemiology, and methods of control.
Prerequisites: A course in vertebrate physiology and/or biochemistry.
Description: Mammalian endocrine glands from the standpoint of their structure, their physiological function in relation to the organism, the chemical nature and mechanisms of action of their secretory products, and the nature of anomalies manifested with their dysfunction.
Description: Fundamental consideration of cellular and humoral mechanisms of immunity, the structure and function of immunoglobulins, antigen-antibody interactions; hypersensitivity; transplantation and tumor immunity; immune and autoimmune disorders.
This course is a prerequisite for: VBMS 910
Prerequisites: 3 hours of BIOS or 3 hours of LIFE; 3 hours of CHEM
Description: Lectures and discussions of primary literature regarding microorganisms and their role transforming Earth through geologic time.
Description: Nature, physiology, and interactions of microorganisms in foods. Introduction to food-borne diseases, the effect of food processing systems on the microflora of foods, principles of food preservation, food spoilage, and foods produced by microorganisms. Food plant sanitation and criteria for establishing microbial standards for food products.
Description: Biological diversity from an evolutionary perspective. The history of the study of human physical growth and biological principles of growth. Genetic, epigenetic and hormonal effects on human and other mammal growth patterns, and environmental factors that influence growth. Effects of nutrition, disease, socio-economic status, pollution, etc. Unique features of human growth in its various stages. How anthropologists interpret variation in growth patterns among human populations and the possible adaptive significance of this variation.
Description: Plant growth and development specifically of woody plants as viewed from an applied whole-plant physiological level. Plant growth regulators, structure and secondary growth characteristics of woody plants, juvenility, senescence, abscission and dormancy.
Description: Conservation and management of native and invasive predators. Functional and numerical responses. Evolution of predator-prey interactions. Optimal foraging. Modeling predator-prey population dynamics. Trophic cascades. Prey defenses against predation.
Description: Nature and characteristics of populations and communities. Interactions within and between populations in community structure and dynamics. Direct and indirect interactions and ecological processes, competition, predation, parasitism, herbivory, and pollination. Structure, functioning and persistence of natural communities, foodweb dynamics, succession, and biodiversity.
Description: Biological systems, from molecules to ecosystems, are analyzed using mathematical techniques. Strengths and weaknesses of mathematical approaches to biological questions. Brief review of college level math; introduction to modeling; oscillating systems in biology; randomness in biology; review of historically important and currently popular models in biology.
Prerequisites: 12 hrs BIOS, including BIOS/NRES 220/BIOS220x; two semesters CHEM.
Description: Physical, chemical, and biological processes that occur in fresh water. Organisms occurring in fresh water and their ecology; biological productivity of water and its causative factors; eutroplication and its effects.
Prerequisites: One semester microbiology; one semester biochemistry or organic chemistry.
Description: Soil from a microbe's perspective-growth, activity and survival strategies; principles governing methods to study microorganisms and biochemical processes in soil; mechanisms controlling organic matter cycling and stabilization with reference to C, N, S, and P; microbial interactions with plants and animals; and agronomic and environmental applications of soil microorganisms.
Description: Introduction to animal behavior stressing the ethological approach. Anatomical and physiological bases of behavior, ontogenetic and phylogenetic observations, and the relations of animal behavior studies to genetics, ecology, taxonomy, and evolution.
Prerequisites: BIOS/NRES 489/889 or equivalent.
Description: Biology of fishes. Factors that affect fishes in the natural environment. Techniques used in the analysis and management of fish populations.
Prerequisites: PSYC 273 or PSYC 373 or BIOS 373.
Description: Relationship of physiological variables to behavior, an introduction to laboratory techniques in neuropsychology.
Prerequisites: NRES 859 or equivalent
Description: In-depth consideration of selected areas of limnology including stream limnology, primary production, secondary production, nutrient cycling, and eutrophication.
BIOS 207 or BIOS 220 recommended. Offered summers only at Cedar Point Biological Station.
Description: Behavior of animals. Stresses methods for testing evolutionary hypotheses under field conditions with emphasis on foraging behavior, animal communication, and animal social systems.
Prerequisites: BIOS 207 or equivalent.
Extensive field work is required.
Description: Structure, function, and distribution of communities. Interaction of different species with their biotic and abiotic environments.
Description: Overview of the diversity of plants and algae, with emphasis on phylogenetic relationships, the evolution of important physical and genomic characteristics, principles of plant classification and identification, and modern methods of plant molecular systematics. Lab work on taxonomic analysis and plant identification.
Prerequisites: BIOS/NRES 386 and permission. BIOS 388 recommended.
Description: Fossil and living amphibians and reptiles. Anatomy, classification, ecology and evolution.
May also be offered at Cedar Point Biological Station.
Description: Biology of birds emphasizing the behavior and ecology of this group. Topics include avian diversity, systematics & evolutionary history, flight, foraging, migration, communication, reproductive biology, population ecology and conservation biology.
Prerequisites: Parallel registration in BIOS 475/875
Description: Avian field identification in diverse prairie, riparian, and montane habitats. Individual studies of foraging behavior, territoriality, anti-predator behavior, mating systems, or nesting ecology.
May also be offered at Cedar Point Biological Station. Field trips are required and may occur outside of scheduled class time. Lab and field time emphasize diversity of mammalian families and species identification of Nebraska mammals.
Description: Evolution, natural history, ecology, and functional morphology of planetary mammals and mammals of the Northern Great Plains.
Statistics course recommended.
Description: Pairwise and multiple alignments, sequence similarity and domain search, distance estimation, phylogenetic methods, gene mining, protein classification and structure. Algorithms used in bioinformatics as well as fundamental concepts of molecular evolution that underlie various bioinformatics methods.
Prerequisites: 8 hrs biological sciences
BIOS 109 recommended.
Description: Development, structure, and function of tissues and organs of the higher plants. Relationships of structure to physiology and ecology of plants.
Description: Processes involved in plant growth and development, seed formation, dormancy, germination, differential growth, flowering, and senescence. The role of extrinsic factors (e.g. light, water, and gravity) and intrinsic factors (e.g. formones, pigments, and energy sources) on these processes.
Prerequisites: 12 hrs biological sciences.
Offered only at Cedar Point Biological Station.
Description: Field course in insect taxonomy and biology emphasizing field collection, specimen preparation, classification, and insect natural history.
Prerequisites: 12 hrs biological sciences.
Description: Biology and ecology of aquatic insects.
Prerequisites: CHEM 471/871 or 481/881.
Description: Applications of thermodynamics to biochemical phenomena, optical properties of proteins and polynucleotides, and kinetics of rapid reactions.
Four credit hours may be counted toward the undergraduate BIOS major. Before registering, arrangements must be made with a School of Biological Sciences faculty member to reach an agreement on the scope and to determine the amount of credit for the project.
Description: Independent study and laboratory or field investigation of a specific problem.
Prerequisites: Admission to masters degree program and permission of major adviser
Description: Effects of various mutations on developing biological systems. Mechanisms by which the abnormal genome expresses its pheno-type. Special consideration to vertebrate organisms.
Description: Aimed at improving research design in evolutionary biology. Experience with presenting scientific ideas, as well as help with specific project.
Description: The mechanisms by which DNA and RNA viruses evolve. The relationships between virulence, attenuation and host selection. Transfer of genetic material between virus and host. Evolution of HIV leading to escape from immunologic pressure or drug selection.
Description: Viral oncogenes and the cellular pathways that they influence. The mechanisms by which DNA and RNA viruses cause cancer. Discovery of novel tumor viruses.
Description: Theory and methodology of phylogenetic inference based on molecular characters (mainly DNA sequences). Population genetic principles and analysis of microsatellite loci. Emphasis on project design, data analysis, and hypothesis testing. Training on current computer programs for phylogenetic analysis acquired.
Prerequisites: BIOC/BIOS/CHEM 832 or BIOC/BIOS/CHEM *839
Description: Protein structure and function.
Prerequisites: BIOC/BIOS/CHEM 432/832, or BIOC/BIOS/CHEM *839
Description: Kinetics regulation and reaction mechanisms of enzymes.
Prerequisites: BIOC/BIOS/CHEM 832 or permission
Description: Detailed examination of dynamic control mechanisms of genome maintenance and gene regulation. Mechanisms of transcription, translation, and replication based on analysis of current and seminal literature.
Prerequisites: BIOC/CHEM/BIOS 432/832 and permission
Description: Current metabolic research at the bioenergetic, metabolomic, and molecular level. The normal metabolic processes that go awry in cancer, obesity, and oxidative stress.
Description: Prokaryotic gene regulation, DNA exchange, DNA recombination and repair, comparative prokaryotic genomics and computer-based methods of analysis.
Prerequisites: BIOS 820
Description: Role of RNA in regulation of gene expression and in determining genome structure. Regulation of mRNA stability and function, RNA as regulatory molecules and enzymes, and computer-based methods of analysis.
BIOS 840 recommended.
Description: Biosynthetic activity of bacteria, yeasts, and fungi, including genetically engineered organisms: antibiotic, amino acid, enzyme, and vitamin production; polysaccharides, steroid transformation, microbes as food sources, microbial insecticides, petroleum microbiology, fermentation engineering, and mass production of microbial cells.
Description: Surveys the kinds of quantitative problems that arise in biological research, particularly in field-oriented disciplines such as ecology, evolution and behavior, and the quantitative methods used to solve them. Practical learning of the strengths and weaknesses of different methods through the analysis of biological data on microcomputers.
Description: Covers the use of maximum likelihood and Bayesian analysis in analyzing ecological data broadly defined. A conceptual understanding of the statistical tools is emphasized as well as a practical experience of conducting the analysis using real data and current software.
Description: Ecological phenomena in populations. Quantitative description of population processes, life history strategies, foraging theory, resource interactions, population dynamics of competition and predation, and selected current topics in population ecology. Research methodology and historical development of the field as well as analysis, criticism, and synthesis of current research in the area.
Description: Major aspects of molecular/physiological adaptation in plants and animals including the evolution of metabolic pathways, enzyme function, and gene regulation.
Description: Fundamentals of network theory as it applies to ecology and evolution. A conceptual foundation for analyzing relational data focusing on ecological and social networks in non-human animals.
Description: Ecological and evolutionary forces responsible for patterns of numbers and types of species which coexist and form ecological communities. Mathematical models, coevolution, random processes, historical background, and examination of biotic interactions responsible for the observed patterns. Emphasis on critique and synthesis of current theory in light of empirical evidence.
Description: Methods and principles of systematics and nomenclature.
Prerequisites: BIOS 804
Description: Course work in physics recommended. Advanced introduction to the evolution of animal communication. Addresses evolution of signal structure (including acoustic, visual, electrical, and chemical signals), environmental effects on signal transmission, and the evolution of receiver responses to signals.
Prerequisites: BIOS 820.
Description: Molecular basis of genetics in eukaryotes. Gene structure and regulation, transposable elements, chromosome structure, DNA replication and repair mechanisms and recombination.
Description: Gain practical knowledge of the R programming language for statistical analysis, graphics, data management and simulations in the biological sciences.
Prerequisites: Permission of instructor and departmental Graduate Committee
Description: Research other than thesis.
Description: Reviews of specialized subject areas. Subject dependent on student demand and availability of staff.
Prerequisites: Admission to doctoral degree program and permission of supervisory committee chair